Abstract
Multinucleate Cell Angiohistiocytoma (MCA) is a rare and benign cutaneous condition, reported in fewer than 250 cases in the literature. It is characterized by the proliferation of histiocytes and blood vessels, along with multinucleated giant cells. The exact cause of MCA is not fully understood, although some cases have been linked to trauma, neoplasms, and inflammatory conditions. Typically, MCA presents as asymptomatic, flesh-colored to reddish-brown papules or nodules on the hands, lower extremities, trunk, or head and neck region. In this report, we describe a case of MCA in an 83-year-old male who underwent coronary artery bypass grafting (CABG) surgery and subsequently developed linearly distributed purplish to dark brown papules and nodules on both thighs. The lesions had been progressively increasing in size and number for the past three years, but the patient did not report any other symptoms. A biopsy confirmed the diagnosis of MCA. MCA is generally considered a benign condition that usually does not require medical intervention, although some patients may seek treatment for cosmetic reasons. Various treatment modalities have been reported, including surgical excision, laser therapy, and cryotherapy. However, the optimal management of MCA remains unclear due to its rarity. This case emphasizes the importance of considering MCA as a potential diagnosis in patients presenting with similar cutaneous lesions following CABG surgery. Further research is needed to better understand the etiology, natural history, and optimal management of this rare condition.