Abstract
Pseudolymphomatous folliculitis is a rare subtype of cutaneous lymphoid hyperplasia which shares many characteristics with various types of cutaneous lymphoma. It presents as a dome-shaped nodule, usually on the face, upper trunk, or back. Upon biopsy, one can see lymphocytic infiltration and hyperplasia of the hair follicle as well as many other nonspecific findings such as the presence of perifollicular S-100 staining cells, CD1a positive cells, and granulomas. In most cases, lymphocytic infiltration is primarily of T-cell origin, with CD4 counts present at higher numbers than CD8, though the infiltrate may be of B cell origin in some cases. A unique characteristic of pseudolymphomatous folliculitis is its tendency to quickly and spontaneously regress, often after only incisional biopsy. Although pseudolymphomatous folliculitis shares characteristics of cutaneous lymphoma, it is distinct due to its abrupt onset, short duration, and tendency to spontaneously regress. It is generally treatable with either incisional biopsy or topical corticosteroids, in contrast to cutaneous lymphomas which may be more refractory to treatment. In our case, complete regression of the plaque occurred after three months of topical halobetasol treatment. While these cases do not typically recur, patients should be followed due to the small potential for recurrence. Herein we present a case of pseudolymphomatous folliculitis in a 54-year-old female.
Financial Disclosure:
No current or relevant financial relationships exist.