Abstract
Alopecic and aseptic nodules of the scalp (AANS) is an uncommon but emerging clinical entity characterized by dome-shaped, alopecic nodules that release aseptic contents when aspirated.(1,2) We present two cases of AANS in Black men. The first case is a 34-year-old man with an 8-month history of a rapidly growing solitary nodule with overlying alopecia on the scalp vertex. The second case is a 59-year-old man with an 18-month history of multiple painless and pruritic scalp nodules on the occiput. In each case, the diagnosis was based on clinical and histopathologic findings typical of AANS. Treatment with doxycycline resulted in regression of lesions within two months in both cases. AANS most closely resembles dissecting cellulitis of the scalp (DCS)(3,4) since both share several clinical and histopathologic features and therapeutic strategies.(6) In the recent literature on the topic, efforts have been made to “split” AANS from DCS, defining it as a separate entity. However, we feel that the striking similarities in both the histopathologic and clinical features require that AANS and DCS be reunited as a single entity, existing on a spectrum. We will describe our two cases to highlight the histopathology and recent literature on DCS and AANS in support of our proposal that AANS is a forme fruste of DCS.
Financial Disclosure:
No current or relevant financial relationships exist.