Abstract
Atypical fibroxanthoma-like amelanotic melanoma is a very rare form of melanoma described in the literature [1,2,3] that creates many problems in terms of differential diagnosis. In particular, this melanoma can mimic many skin cancers and benign skin lesions [3], and its correct diagnosis is of fundamental importance for the nosographic classification of the lesion, its correct oncological management, and therefore, the best possible outcome for the patient. We report on a rare case of melanoma with the morphological characteristics of atypical fibroxanthoma (AFX) that clinically resembled a fibrohistiocytic lesion and that caused diagnostic problems in our practice. We also review the current literature with particular emphasis on the clues that can reduce the possibility of, if not avoid, diagnostic error.
Financial Disclosure:
No current or relevant financial relationships exist.