Abstract:

Both metastatic cutaneous endometrial carcinoma and subungual metastases are both rare. Cutaneous metastasis as a presentation of an internal malignancy is uncommon, <1%. The frequency of cutaneous metastasis parallels the most common internal malignancies. Endometrial carcinoma is the most common gynecologic cancer, but cutaneous metastasis is uncommon. Cutaneous metastasis is a harbinger of metastatic disease, and a dismal prognosis. Contrasting with skin metastasis, subungual metastasis is more likely to be an initial or coincidental manifestation of internal malignancy. Primary tumors with subungual metastasis are most commonly lung (40%), genitourinary (17%, with renal cancer representing a majority), and breast (9%). Symptomatology and morphology of subungual metastasis varies. Subungual metastasis is a harbinger of internal metastasis with 80% of those affected dying within <6-months. Herein we present an exceptionally rare case of subungual metastasis of endometrial carcinoma.

Financial Disclosure:
No current or relevant financial relationships exist.

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John Linabury, DO