Abstract:

A 76-year-old female patient presented with a peculiar new skin lesion on the left hallux. Due to its atypical appearance the neoplasm was biopsied. Histologic sections demonstrated numerous thickened, anastomosing cord-like structures composed of bland appearing adnexal keratinocytes. Nearby areas exhibited papillomatosis, epidermal acanthosis, dense hyper/parakeratosis and hypergranulosis. A p16 stain was positive in many of the superficial epidermal keratinocytes. HPV typing was also performed and was negative for low and high-risk HPV (genital types). We herein present an unusual case of a skin lesion which combines features of a poroma with a verruca plantaris. We further review what is known of the relationship between HPV and poroid neoplasms.

Financial Disclosure:
No current or relevant financial relationships exist.

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Diana Kneiber, MD