Track

Case Reports

Abstract

Herein, we report two cases of sporadic papillary hemangioma. The first case was a 66-year-old female with a lesion on the right posterior parietal scalp. A biopsy of the lesion showed lobulated vascular proliferation in the dermis and subcutaneous tissue, composed of a papillary arrangement of vascular spaces that were lined by plump endothelial cells with numerous densely eosinophilic globules. The second case was from a 72-year-old male, who presented with a long-standing nodule on his left cheek that demonstrated increased vessels in a lobular and papillary configuration with endothelial cells containing similar eosinophilic, hyaline globules. Papillary hemangioma is a rare benign cutaneous vascular tumor predominantly seen in the head & neck region, that clinically presents as a solitary erythematous or bluish papulonodule. On histopathology, the lesions show a papillary architecture with blood vessels that contain eosinophilic globules (presumed to occur due to lysosomal degradation) within endothelial cells. These eosinophilic globules are similar to those seen in glomeruloid hemangioma, a vascular lesion that occurs in Polyneuropathy, Organomegaly, Endocrinopathy, M-protein spike, and Skin changes (POEMS) syndrome, often associated with Castleman disease. The two cases presented here did not have any syndromic association. This study highlights two cases of a rare variant of cutaneous hemangioma that shows features overlapping with glomeruloid hemangioma.