Abstract

Polymethylmethacrylate (PMMA) is a rigid, transparent and colorless, thermoplastic polymer widely utilized in plastic surgery, orthopedic surgery and dentistry. Notably, it serves as a dermal filler, effecting wrinkle correction, augmenting lip volume, ameliorating acne scars, as well as functioning as a substance for bone cements, among other applications. Within the realm of nasal surgery, PMMA injections have found application in addressing post-rhinoplasty asymmetries or, predominantly, in the context of non-surgical rhinoplasty procedures. We report a case of a 60-year-old woman with a history of cosmetic nasal surgery performed outside of the US who presented with a nasal dorsum mass. The lesion was concernig for malignancy and biopsied.  Histopathological examination showed prominent crystalline debris associated with foreign body giant cell granulomatous reaction. Subsequent inquiry uncovered the intrinsic utilization of PMMA during the past surgical procedure, a practice that is currently uncommon. Clinicopathological correlation was crucial in establishing the diagnosis of this unusual foreign body.