Abstract

Nodular Fasciitis is a relatively common mesenchymal neoplasm that is considered a self-limited, benign neoplasm of fibroblastic/myofibroblastic lineage of differentiation. Other variants of nodular fasciitis are intravascular fasciitis and cranial fasciitis. NF was previously named as pseudosarcomatous fasciitis referring to the fact that this tumor can mimic sarcomatous neoplasms. NF can occur in a wide range of ages commonly between 20-40 years with no significant sex predilection. Tumors appear to be sporadic and of unknown etiology. We report an unusual case presentation of nodular fasciitis, the patient originally presented with a small subcutaneous mass in the upper inner thigh which was initially diagnosed as nodular fasciitis then the mass increased in size rapidly over the following two months and rebiopsy showed myofibroblastic sarcoma/ pleomorphic fibroblastic sarcoma ( grade 3). This unique presentation raised the question of misdiagnosis versus malignant transformation of the initial preliminary diagnosis of nodular fasciitis.