Abstract

A 58-year-old man presented with a 2-month history of a raised lesion on the right hand. Clinical examination demonstrated an annular pink plaque with raised borders and central erosion on the right dorsal hand. Histopathologic examination demonstrated well differentiated superficially invasive squamous cell carcinoma present within the superficial dermis centrally. In addition, there was surrounding granulomatous dermatitis characterized by palisading histiocytes around an area of central necrobiosis with focally increased mucin. These findings were consistent with invasive well-differentiated squamous cell carcinoma (SCC) with surrounding granuloma annulare (GA). This case highlights a unique presentation in which clinical pathologic correlation is critical prior to arriving at a correct diagnosis.

Financial Disclosure:
No current or relevant financial relationships exist.